Uparel XR 15MG Tablets contain Upadacitinib 15mg, an extended-release Janus kinase (JAK) inhibitor used to manage selected inflammatory conditions, particularly moderate-to-severe rheumatoid arthritis and other specialist-diagnosed inflammatory joint disorders. Uparel XR 15MG Tablets may help reduce inflammation, joint pain, swelling, and stiffness by modifying immune-system signals involved in inflammation.