Description
Product Information
- Product Name: Eplic (Carbamazepine) 200mg 50-Tablets
- Generic Name: Carbamazepine
- Strength: 200mg per tablet
- Dosage Form: Tablet
- Pack Size: 50 tablets
- Medicine Category: Antiepileptic / Anticonvulsant
- Company: Cell Laboratories Pvt Ltd.
- Suitable for: Appropriately diagnosed adults or children with certain seizure disorders and patients with trigeminal neuralgia
- Prescription Status: Prescription medicine
- Price: PKR 500
Composition of Eplic (Carbamazepine) 200mg 50-Tablets
Each tablet contains:
Eplic (Carbamazepine) 200mg 50-Tablets belongs to the anticonvulsant group of medicines. Carbamazepine is also a specific treatment for the characteristic nerve pain caused by true trigeminal neuralgia.
What is Eplic (Carbamazepine) 200mg 50-Tablets?
Eplic (Carbamazepine) 200mg 50-Tablets is a prescription neurological medicine containing Carbamazepine. It works mainly by reducing repeated abnormal electrical impulses in nerve cells, helping stabilize electrical activity in the brain.
Carbamazepine has established anticonvulsant use in partial or focal seizures, generalized tonic-clonic seizures, and certain mixed seizure patterns. It is also indicated for pain associated with true trigeminal neuralgia.
Eplic (Carbamazepine) 200mg 50-Tablets should not be used as an ordinary painkiller. It is not intended for routine headaches, muscle aches, dental pain, or other minor pains.
Is Carbamazepine suitable for every type of seizure?
No. Carbamazepine does not effectively control absence seizures and may not be suitable for every epilepsy syndrome. A neurologist or physician should identify the seizure type before selecting treatment.
Uses & Benefits of Eplic (Carbamazepine) 200mg 50-Tablets
Eplic (Carbamazepine) 200mg 50-Tablets may be prescribed for:
- Partial or focal seizures
- Complex partial seizures
- Generalized tonic-clonic seizures
- Certain mixed seizure patterns
- Long-term management of appropriately diagnosed epilepsy
- Pain caused by true trigeminal neuralgia
- Selected cases of glossopharyngeal neuralgia under specialist supervision
Carbamazepine may be used alone or together with other antiepileptic medicines depending on the seizure type, treatment response, and medical history.
Carbamazepine is also used by specialists in selected patients with mood disorders such as bipolar disorder. However, its role, dosage, and approved indication can vary by formulation and jurisdiction, so Eplic (Carbamazepine) 200mg 50-Tablets should only be used for this purpose when specifically prescribed by a psychiatrist or other qualified physician.
Who Should Use This?
Eplic (Carbamazepine) 200mg 50-Tablets may be prescribed for adults or children with a physician-confirmed condition for which Carbamazepine is appropriate.
This can include:
- Adults with partial or generalized tonic-clonic seizures
- Children with an appropriate seizure disorder
- Patients requiring ongoing Carbamazepine therapy for epilepsy
- Patients diagnosed with true trigeminal neuralgia
- Patients whose neurologist determines that Carbamazepine is an appropriate anticonvulsant
For children, dosage depends strongly on age, body weight, seizure type, and clinical response. A 200mg tablet may not be the appropriate formulation or dose for every child.
How to Use / Dosage
Eplic (Carbamazepine) 200mg 50-Tablets must be taken exactly as prescribed by the physician. Carbamazepine dosing is individualized and usually begins at a lower dose followed by gradual adjustment.
Reference prescribing information for conventional Carbamazepine tablets provides the following general epilepsy dosing framework:
- Adults and children over 12 years: an initial dose of 200mg twice daily may be used, followed by gradual physician-directed increases.
- Children 6–12 years: treatment may begin at 100mg twice daily, requiring an appropriate tablet strength or formulation.
- Children under 6 years: dosing is calculated according to body weight, commonly beginning at 10–20mg/kg/day in divided doses.
Carbamazepine should generally be taken with meals. The physician should adjust treatment to the lowest dose that adequately controls symptoms.
These figures are general prescribing references, not individualized dosage instructions. Do not use them to calculate a dose without a physician, particularly for children.
Dosage for trigeminal neuralgia
Carbamazepine treatment for trigeminal neuralgia generally begins at a lower dose and is gradually adjusted until pain is controlled. The treating doctor should use the lowest effective maintenance dose.
Can Eplic be stopped after seizures improve?
No. Eplic (Carbamazepine) 200mg 50-Tablets should not be stopped suddenly. Abrupt withdrawal of an antiepileptic medicine can increase seizure frequency and potentially lead to serious complications. Carbamazepine should be reduced gradually under medical supervision.
Price in Pakistan
Price in Pakistan: PKR 500
The listed price applies to Eplic (Carbamazepine) 200mg 50-Tablets, containing 50 tablets per pack. The final retail price may vary slightly according to pharmacy, city, and stock availability in Pakistan.
Precautions & Side Effects of Eplic (Carbamazepine) 200mg 50-Tablets
Carbamazepine requires careful medical supervision because it can cause clinically important side effects and interactions.
Before taking Eplic (Carbamazepine) 200mg 50-Tablets, tell the physician if the patient:
- Has liver or kidney disease
- Has previously had a blood or bone-marrow disorder
- Has heart disease or conduction abnormalities
- Has glaucoma or raised pressure inside the eye
- Has low blood sodium
- Has hepatic porphyria
- Has experienced a serious medicine-related skin reaction
- Is pregnant or planning pregnancy
- Is breastfeeding
- Takes other antiepileptic, psychiatric, antibiotic, antifungal, cardiovascular, or anticoagulant medicines
Serious skin reaction warning
Carbamazepine can rarely cause potentially life-threatening skin reactions, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).
The HLA-B1502 genetic variant is associated with increased SJS/TEN risk in genetically susceptible populations. Current prescribing information recommends testing before starting Carbamazepine in patients whose ancestry comes from populations where HLA-B1502 may occur.
Seek urgent medical attention for:
- A new or spreading rash
- Skin blistering or peeling
- Mouth ulcers or sores
- Fever accompanied by rash
- Facial swelling
Blood-related warning
Carbamazepine has been associated with rare cases of aplastic anemia and agranulocytosis. A baseline complete blood count may therefore be recommended before treatment, with additional monitoring when clinically appropriate.
Report symptoms such as persistent fever, unusual infections, sore throat, unexplained bruising, or unusual bleeding promptly.
Low sodium warning
Carbamazepine may cause hyponatremia or abnormally low blood sodium, sometimes due to SIADH. Symptoms may include headache, confusion, weakness, poor concentration, unsteadiness, or increased seizure frequency. Older patients and people taking diuretics may have a higher risk.
Common side effects
Possible side effects include:
- Dizziness
- Drowsiness
- Unsteadiness
- Nausea
- Vomiting
- Headache
- Blurred or double vision
Dizziness and drowsiness can affect activities requiring alertness. Patients should understand how Eplic (Carbamazepine) 200mg 50-Tablets affects them before driving or operating machinery.
Important Medicine Interactions
Carbamazepine interacts with many medicines because it affects liver enzymes involved in drug metabolism.
Tell the doctor about all prescription medicines, OTC medicines, vitamins, and herbal products, particularly:
- Other antiepileptic medicines
- Certain antibiotics
- Certain antifungal medicines
- Antidepressants and psychiatric medicines
- Warfarin and other anticoagulants
- Some heart and blood-pressure medicines
- Hormonal contraceptives
- Rifampicin
- Medicines that can cause drowsiness
Carbamazepine can reduce the effectiveness of hormonal contraceptives, so patients who can become pregnant should discuss appropriate contraception with their physician.
Avoid grapefruit or grapefruit juice unless the treating physician specifically approves it, as it may increase Carbamazepine exposure.
Pregnancy and Breastfeeding
Carbamazepine can cause fetal harm and has been associated with congenital abnormalities, including neural-tube defects. Patients who are pregnant, planning pregnancy, or could become pregnant should discuss treatment with their neurologist or physician.
A patient taking Eplic (Carbamazepine) 200mg 50-Tablets for epilepsy should not suddenly stop treatment after discovering a pregnancy. Uncontrolled seizures and abrupt medicine withdrawal can also be dangerous. The treating physician should urgently review the treatment plan.
Breastfeeding patients should also discuss the benefits and potential risks with their healthcare professional.
Monitoring During Treatment
Patients using Eplic (Carbamazepine) 200mg 50-Tablets may require periodic monitoring that can include:
- Complete blood count
- Liver-function tests
- Kidney-function assessment
- Blood sodium
- Carbamazepine blood concentrations when clinically necessary
- Assessment for skin reactions
- Review of seizures and treatment response
Blood-level monitoring can help improve the safety and effectiveness of Carbamazepine therapy in selected patients.
Frequently Asked Questions (FAQs)
What is the price of Eplic (Carbamazepine) 200mg 50-Tablets in Pakistan?
Price in Pakistan: PKR 500. Each pack contains 50 tablets, although the final retail price may vary according to the pharmacy and location.
What are the uses of Eplic (Carbamazepine) 200mg 50-Tablets?
Eplic (Carbamazepine) 200mg 50-Tablets are used for certain partial and generalized tonic-clonic seizures and for pain associated with true trigeminal neuralgia.
Is Eplic (Carbamazepine) 200mg 50-Tablets safe for children with epilepsy?
It may be prescribed to children when Carbamazepine is suitable for their seizure type. However, pediatric doses are based on age, body weight, and clinical response, and the 200mg tablet strength may not be appropriate for every child.
Is Eplic (Carbamazepine) 200mg 50-Tablets a painkiller?
It is not a general painkiller. Carbamazepine has a specific role in relieving pain associated with true trigeminal neuralgia and should not be used for routine aches or pains.
Can Eplic (Carbamazepine) 200mg 50-Tablets be stopped suddenly?
No. Sudden discontinuation can cause seizures to return or worsen. Any dose reduction or discontinuation should be supervised by the treating physician.
Pakistan Medicine-Safety Information
Eplic (Carbamazepine) 200mg 50-Tablets is a prescription medicine and must be used only on a doctor’s recommendation. Patients, caregivers, and healthcare professionals in Pakistan can report suspected adverse reactions through DRAP’s official pharmacovigilance system.
DRAP Adverse Events Reporting System
Drug Regulatory Authority of Pakistan (DRAP)
Medical Disclaimer
This information is provided for patient education and product-information purposes only. It does not replace diagnosis, neurological assessment, laboratory testing, dosage selection, or medical follow-up.
Eplic (Carbamazepine) 200mg 50-Tablets must be used only on the prescription of a registered medical practitioner. Never start, stop, increase, or reduce Carbamazepine treatment without consulting the treating physician.
