Co-Vmed 10mg/160mg/12.5mg Tablets

Description

Product Information

• Product name: Co-Vmed 10mg/160mg/12.5mg
• Generic name: Amlodipine BP/Valsartan USP/Hydrochlorothiazide USP
• Dosage form: Tablet
• Product type: Triple-combination antihypertensive
• Target audience: Adult patients with high blood pressure requiring triple antihypertensive therapy
• Therapeutic classes: Calcium Channel Blocker + Angiotensin II Receptor Blocker + Thiazide Diuretic
• Prescription status: Prescription medicine
• Price: PKR 650

Composition of Co-Vmed

Each Co-Vmed tablet contains:

• Amlodipine Besylate equivalent to Amlodipine BP 10mg
• Valsartan USP 160mg
• Hydrochlorothiazide USP 12.5mg

The 10mg/160mg/12.5mg strength is a recognized fixed-dose combination of Amlodipine, Valsartan, and Hydrochlorothiazide.

What is Co-Vmed?

Co-Vmed is a triple-combination prescription medicine used to manage hypertension, commonly known as high blood pressure. Co-Vmed combines three medicines that lower blood pressure through different mechanisms:

• Amlodipine: A calcium channel blocker
• Valsartan: An angiotensin II receptor blocker, or ARB
• Hydrochlorothiazide: A thiazide diuretic or water tablet

Amlodipine helps widen blood vessels, Valsartan blocks signals that cause blood vessels to tighten, and Hydrochlorothiazide helps the kidneys remove excess sodium and water. Together, these actions help Co-Vmed lower blood pressure in patients who require triple therapy.

Fixed-dose Amlodipine, Valsartan, and Hydrochlorothiazide combinations are generally used as add-on, switch, or replacement treatment when two antihypertensive classes do not provide adequate control. They are not generally indicated as the initial treatment for newly diagnosed hypertension.

Uses & Benefits of Co-Vmed

Co-Vmed is used for the treatment of hypertension in adult patients who require three blood-pressure medicines.

Main uses of Co-Vmed include:

• Management of uncontrolled high blood pressure
• Triple antihypertensive therapy when two medicines are insufficient
• Replacement of separately prescribed Amlodipine, Valsartan, and Hydrochlorothiazide
• Helping relax narrowed blood vessels
• Reducing excess sodium and fluid
• Supporting once-daily blood-pressure management
• Reducing the number of separate tablets required

By lowering blood pressure, Co-Vmed may contribute to reducing the general risk of cardiovascular events associated with uncontrolled hypertension. The benefit depends on regular use, appropriate monitoring, and management of other cardiovascular risk factors.

How Does Co-Vmed Work?

Amlodipine 10mg

Amlodipine relaxes the muscle in blood-vessel walls by reducing calcium entry into the cells. This widens the blood vessels and allows blood to flow with less resistance.

Valsartan 160mg

Valsartan blocks the action of angiotensin II, a substance that can cause blood vessels to narrow. Blocking this action helps the blood vessels remain relaxed.

Hydrochlorothiazide 12.5mg

Hydrochlorothiazide is a diuretic that increases the removal of excess sodium and water through urine. This reduces excess circulating fluid and helps lower blood pressure.

The three components of Co-Vmed act together to provide additional blood-pressure reduction for patients who require triple treatment.

Who Should Use This?

Co-Vmed is intended for adult patients with high blood pressure who require triple antihypertensive therapy.

A physician may prescribe Co-Vmed for:

• Adults whose blood pressure remains uncontrolled with two medicines
• Patients already taking an ARB, calcium channel blocker, and diuretic
• Patients switching from separately prescribed Amlodipine, Valsartan, and Hydrochlorothiazide
• Adults requiring the 10mg/160mg/12.5mg strength
• Patients for whom once-daily triple therapy is medically appropriate

Co-Vmed should not be selected based on a single high reading or used without medical supervision. A physician may assess repeated blood-pressure readings, kidney function, electrolyte levels, medical history, and current medicines before prescribing it.

How to Use / Dosage

Take Co-Vmed exactly as prescribed by your physician.

General dosage guidance

• Co-Vmed is typically taken once daily.
• It may be taken with or without food.
• Take the tablet at approximately the same time each day.
• Swallow the tablet with water.
• Do not take more than the prescribed dose.
• Do not switch strengths without medical advice.
• Do not stop Co-Vmed because your blood-pressure reading has improved.

The dosage may be adjusted according to the patient’s response and tolerance. The reference prescribing information states that the full blood-pressure-lowering effect of the maximum regimen may take approximately two weeks to develop.

What should you do if you miss a dose?

Take the missed dose when you remember. When it is almost time for the next scheduled dose, skip the missed tablet and continue with your normal schedule. Do not take two Co-Vmed tablets together unless specifically directed by a physician.

Price in Pakistan

Price in Pakistan: PKR 650

The listed Co-Vmed price may vary slightly according to the pharmacy, city, stock availability, or retailer. Purchase Co-Vmed from a licensed and reliable pharmacy.

Who should not use Co-Vmed?

Co-Vmed should not be used by patients with:

• Anuria, meaning an inability to produce urine
• Known hypersensitivity to any ingredient
• Hypersensitivity to sulfonamide-derived medicines

Co-Vmed should not be combined with aliskiren in patients with diabetes.

Storage Instructions

• Store Co-Vmed at room temperature.
• Protect it from excessive heat and moisture.
• Keep the tablets in their original packaging.
• Keep Co-Vmed out of the sight and reach of children.
• Do not use the tablets after the printed expiry date.
• Follow any additional storage instructions printed on the local packaging.

Comparable Amlodipine, Valsartan, and Hydrochlorothiazide tablets are stored at 20°C to 25°C, with permitted controlled-room-temperature excursions.

Frequently Asked Questions (FAQs)

What is the price of Co-Vmed in Pakistan?

The listed Co-Vmed price in Pakistan is PKR 650. The final amount may vary slightly according to the pharmacy and stock availability.

What are the uses of Co-Vmed?

Co-Vmed is used to treat high blood pressure in adults who require triple antihypertensive therapy. It may be prescribed when two blood-pressure medicines do not provide adequate control.

Is Co-Vmed safe for high blood pressure patients?

Co-Vmed may be appropriate for selected adult hypertension patients when prescribed by a physician. Kidney function, electrolyte levels, pregnancy status, and medicine interactions should be assessed before and during treatment.

What is the composition of Co-Vmed?

Each Co-Vmed tablet contains Amlodipine 10mg, Valsartan 160mg, and Hydrochlorothiazide 12.5mg.

Can Co-Vmed be taken with food?

Yes. Co-Vmed may generally be taken once daily with or without food. Follow the exact instructions given by the treating physician.

Is Co-Vmed a water tablet?

Co-Vmed contains Hydrochlorothiazide, which is a thiazide diuretic or water tablet. It also contains Amlodipine and Valsartan, making it a triple-combination antihypertensive medicine.

Can pregnant women use Co-Vmed?

No. Co-Vmed contains Valsartan, which may cause serious harm to an unborn baby. Contact the treating physician immediately if pregnancy occurs or is suspected.

Can Co-Vmed be stopped when blood pressure becomes normal?

Do not stop Co-Vmed without consulting your physician. A normal blood-pressure reading may indicate that the medicine is controlling the condition successfully.

Pakistan Medicine-Safety Information

Patients and healthcare professionals can report suspected side effects through the DRAP Adverse Events Reporting System. DRAP accepts reports through its official Med Vigilance e-reporting service.

Hypertension is included among the non-communicable diseases studied in Pakistan. Additional local information is available from the Health Research Institute, National Institutes of Health Pakistan.

Medical Disclaimer

This information is provided for educational purposes only and does not replace diagnosis, treatment, or monitoring by a qualified healthcare professional.

Co-Vmed is a prescription medicine. Use Co-Vmed only on the prescription of a registered medical practitioner. Do not start, stop, or change the dosage without consulting your physician.